ChemicalBook > CAS DataBase List > GLX351322

GLX351322

Product Name
GLX351322
CAS No.
835598-94-2
Chemical Name
GLX351322
Synonyms
CS-2871;GLX 351322;GLX-351322;GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit;Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate;4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester
CBNumber
CB54672882
Molecular Formula
C21H25N3O5S
Formula Weight
431.51
MOL File
835598-94-2.mol
More
Less

GLX351322 Property

solubility 
DMSO:20.0(Max Conc. mg/mL);46.35(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.32(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.76(Max Conc. mM)
Ethanol:4.0(Max Conc. mg/mL);9.27(Max Conc. mM)
form 
A crystalline solid
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2546
Product name
GLX351322
Purity
≥98% (HPLC)
Packaging
5MG
Price
$95.3
Updated
2023/06/20
Sigma-Aldrich
Product number
SML2546
Product name
GLX351322
Purity
≥98% (HPLC)
Packaging
25MG
Price
$385
Updated
2023/06/20
ChemScene
Product number
CS-0018088
Product name
GLX351322
Purity
99.48%
Packaging
25mg
Price
$500
Updated
2021/12/16
ChemScene
Product number
CS-0018088
Product name
GLX351322
Purity
99.48%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0018088
Product name
GLX351322
Purity
99.48%
Packaging
50mg
Price
$850
Updated
2021/12/16
More
Less

GLX351322 Chemical Properties,Usage,Production

Biological Activity

GLX351322 is an inhibitor of NADPH oxidase 4 (NOX4). It can inhibits tetracycline-induced hydrogen peroxide production in NOX4-overexpressing cells with IC50 of 5 μM.

in vitro

GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC 50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells ( IC 50 , 40 μM).

in vivo

GLX351322 (3.8 mg/kg/day, po) ameliorates HFD-induced hyperglycemia in mice.

target

TargetValue
NOX4
(Cell-free assay)		 5 μM

GLX351322 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

GLX351322 Suppliers

China 33 India 1 United States 6 Global 40
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58

835598-94-2, GLX351322Related Search:


  • CS-2871
  • GLX 351322;GLX-351322
  • 4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester
  • GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit
  • Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
  • 835598-94-2